Nuclear weapon
A nuclear weapon is an explosive device that derives its destructive force from nuclear reactions, either fission (fission bomb) or a combination of fission and fusion reactions (thermonuclear bomb), producing a nuclear explosion. Both bomb types release large quantities of energy from relatively small amounts of matter.
The above passage was taken from Wikipedia.
Different species in the Project have their own history involving nukes.
Felin
Like any sufficiently advanced species, the felin figured out how to develop nukes. Around the year 3364, the theory behind the atom bomb was developed far enough to consider practice. A low-yield bomb, approximately 10 kilotons, was detonated on a remote, uninhabited island. Witnessing the result, the team in charge unanimously agreed to not do that again. Even so, the knowledge on how to produce higher yield bombs still exists.
Use of a nuclear weapon was considered during the attack of the Desecrator in 3541. This was vetoed at first, then rendered a non-issue when the combined Rhatai forces proved enough to defeat the beast.
Nation
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Space Huns
Most humans know that atomic theory was developed in Old Earth 1890-1900, and saw militarisation in 1945. The origin country of the Hungarian settlers, Hungary, only had peaceful applications with primitive atomic power plants. Beyond this, most space huns not know the details of atomic weaponry.
After their settlement in the Határmezsgye system, the settlers ensured their freedom with low-yield nuclear weaponry, but only as a final deterrent.